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Covid19

31Aug

Newest COVID-19 Surge Leads to Shortages in Therapeutics

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The resurgence of COVID-19 because of the Delta variant has led to significant imbalances in the supply and demand of commonly used medications for hospitalized patients, including tocilizumab, dexamethasone, baricitinib, and remdesivir. According to a report from Vizient, the average demand for these medications has dramatically increased over recent months, whereas fill rates for hospital […]

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27Aug

What treatments are being used by hospitals to treat COVID?

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WEST PALM BEACH, Fla. — It’s not a one-size-fits-all situation, but local hospitals have developed standard protocols for treating COVID-19. The medicines you receive at the hospital if you are admitted with COVID-19 symptoms depends on many factors. It also depends on what hospital you go to. SPECIAL COVERAGE: Coronavirus Four infectious disease specialists affiliated […]

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26Aug

RWJBarnabas Health Offering Third COVID-19 Dose

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Photo by Micromedia Publications OCEAN COUNTY – RWJBarnabas Health is now offering a third COVID-19 dose for those who are immunocompromised.    The Centers for Disease Control and Prevention (CDC) has recommended that people whose immune systems are moderately to severely compromised should receive a third dose of the mRNA COVID-19 vaccine (Pfizer or Moderna) after […]

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25Aug

JCI – Intravenous bamlanivimab use associates with reduced hospitalization in high-risk patients with mild to moderate COVID-19

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Clinical MedicineIn-Press PreviewVirology Free access | 10.1172/JCI151697 Ravindra Ganesh,1 Colin F. Pawlowski,2 John C. O’Horo,3 Lori L. Arndt,4 Richard F. Arndt,5 Sarah Bell,6 Dennis M. Bierle,1 Molly Destro Borgen,7 Sara Hanson,8 Alexander Heyliger,9 Jennifer L. Larsen,6 Patrick J. Lenehan,10 Robert Orenstein,11 Arjun Puranik,2 Leigh L. Speicher,12 Sidna M. Tulledge-Scheitel,13 AJ Venkatakrishnan,2 Caroline G. Wilker,14 Andrew […]

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24Aug

Oral Remdesivir Could Lower COVID Hospitalizations, Preclinical Study Says

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An oral version of remdesivir is being developed by scientists at the University of California, San Diego (UCSD) to combat the SARS-CoV-2 virus early in its infection cycle. Though still in preclinical trials, results suggest it could reduce disease severity and hospitalizations thanks to its longer half-life, greater efficacy and reduced toxicity when compared to […]

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19Aug

Doctors say monoclonal antibody treatment is ‘the answer’ to preventing hospitalizations

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MONTGOMERY, Ala. (WSFA) – Monoclonal antibody infusions have been used for months in Montgomery, but with COVID-19 case numbers growing, there’s a renewed push for the treatment to prevent further crowding of the city’s hospitals. At a press conference last week, State Health Officer Scott Harris was asked about the best treatment available for people […]

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18Aug

Remdesivir in drugstores? California scientists think they can do it

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Scientists at University of California, San Diego, have developed a way to put remdesivir and other intravenous COVID-19 treatments into a capsule that patients could safely take orally at home, according to a paper in an online issue of Antimicrobial Agents and Chemotherapy. Since the pandemic began, scientists worldwide have been seeking a treatment that […]

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17Aug

FDA Authorizes Use of COVID-19 Antibody Therapy for Postexposure Prophylaxis

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The Food and Drug Administration (FDA) has authorized the use of REGEN-COV (casirivimab and imdevimab) for postexposure prophylaxis of COVID-19 in individuals (12 years of age and older weighing at least 40kg) who are at high risk for progression to severe COVID-19, including hospitalization or death. The investigational agent was previously granted Emergency Use Authorization […]

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15Aug

Fla. woman hospitalized with COVID-19 says struggle changed her for life

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CAPE CORAL, Fla. (WINK) – A Florida woman hospitalized with COVID-19 says her battle has been lonely, scary and preventable. She says if she could go back in time, she would have gotten vaccinated. When COVID-19 first began to spread around her Florida community, Shannon Ruvelas says you wouldn’t catch her without a mask and […]

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14Aug

SARS-CoV-2 variants containing L452R spike mutation more resistant to antibody-mediated neutralization

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A team of scientists from Frankfurt, Germany, has recently explored the efficacy of vaccine- or infection-induced antibodies and therapeutic monoclonal antibodies in neutralizing kappa and delta variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The findings reveal that the delta variant is more resistant to antibody-mediated neutralization than the kappa variant. The study is […]

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14Aug

Atea’s Experimental Antiviral Shows More Promise in Preventing COVID-19

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An antiviral treatment under development by Atea Pharmaceuticals is showing promise against COVID-19. Recently announced interim results from a Phase II study showed that the asset achieved antiviral activity in healthy patients and set the stage for the drug’s potential as a preventative treatment for COVID following exposure to the virus. AT-527 is an oral direct-acting antiviral […]

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