A correlation between asthma and gastroesophageal reflux disease approached statistical significance in a retrospective observational study of 73 patients, researchers said.
The study of patients with bronchodilator response and pathological gastroesophageal reflux disease (GERD) found that as their DeMeester scores increased, FEV1/FVC ratios decreased, indicating some degree of reactive airway disease, Richa Sheth, MD, a second-year resident in the internal medicine program at the University of California, San Diego, told Healio at the American Thoracic Society International Conference. It was the top story in allergy/asthma last week.
In another top story, researchers found rapid, significant reductions to fractional exhaled nitric oxide in patients with asthma using the SAR443765 bifunctional NANOBODY molecule. The reductions were greater than those seen in monovalent treatments, Benjamin T. Suratt, MD, clinical lead at Sanofi, said.
Read these and more top stories in allergy/asthma below:
Relationships between asthma, gastroesophageal reflux disease trend toward significance
A correlation between DeMeester scores and respiratory indicators approached statistical significance in patients with bronchodilator response and pathological GERD. Read more.
Molecule targets TSLP, IL-13 to reduce FeNO in mild to moderate asthma
Patients with asthma experienced fast and substantial reductions in fractional exhaled nitric oxide with the SAR443765 bifunctional NANOBODY molecule, which blocks thymic stromal lymphopoietin and IL-13, according to a study. Read more.
Council formed to advance ‘innovative’ food allergy research, treatments
Uncovering the mysteries of food allergies and developing cutting-edge methods to treat them is the mission of the new scientific advisory council organized by the nonprofit Food Allergy Research & Education. Read more.
Pregnant women with asthma, obstructive sleep apnea have increased airways resistance
Pregnant women who have both asthma and obstructive sleep apnea have increased central airways resistance, but not increased peripheral airways resistance, according to a presentation. Read more.
Vitamin D supplementation during pregnancy, infancy associated with less asthma, wheeze
Vitamin D supplementation during pregnancy and sufficient exposure to vitamin D at age 12 months were associated with less asthma and recurrent wheeze by age 3 years, according to data. Read more.