Idiopathic Pulmonary Fibrosis

Background Laboratory diagnosis of Lyme borreliosis (LB) is mainly based on serology, which has limitations, particularly in the early stages of the disease. In recent years there have been conflicting reports concerning a new diagnostic tool using the cytokine interferon-gamma (IFN-γ). Previous studies have generally found low concentrations of IFN-γ in early LB infection. The […]

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.[5] The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheelock as a product of human leukocytes stimulated with phytohemagglutinin, and by others as a […]

K Punareewattana, L V Sharova, W Li, D L Ward, S D Holladay International Immunopharmacology 2003, 3 (12): 1639-55 14555289 Maternal immune stimulation in mice decreases fetal abnormalities caused by diverse etiologies. Growth factors produced by activated immune cells were proposed to be key mediators that may exert their effects on placenta or embryo. Diabetes […]

The predicted lung function of patients with idiopathic pulmonary fibrosis (IPF) treated with nintedanib as part of the FIBRONET study was stable over 1 year, according to results of a post hoc analysis published in Respiration. The proportion of patients with coughs also decreased, and the safety profile of the treatment was consistent with its […]

NEW YORK – Qiagen said on Monday that its QuantiFeron-TB Gold Plus (QFT-Plus) assay for tuberculosis diagnosis has been approved by China’s National Medical Products Administration. The new approval is for diagnosing both latent and active TB infections and builds on prior regulatory approvals for QFT-Plus in the US and other countries around the world, […]

Catalog Number: USB-A1059-86F Product Overview Article Name: AIF1 (Allograft Inflammatory Factor 1, AIF-1, DASS-82G15.2, G1, IBA1, IRT-1, Em:AF129756.17, Interferon gamma Responsive Transcript, IRT-1, Ionized Calcium-binding Adapter Molecule, Protein G1) (FITC), IgG2b, Clone: 1022-5, Mouse, Biozol Catalog Number: USB-A1059-86F Supplier Catalog Number: A1059-86F Alternative Catalog Number: USB-A1059-86F-50 Manufacturer: US Biological Host: Mouse Category: Antikörper Application: IHC […]

Clone XMG1.2 Isotype Rat IgG1κ Isotype Control Rat IgG1-PACBLU (KLH/G1-2-2) Specificity Mouse IFN-γ Alternative Names Interferon-γ, immune interferon, IIF, type II interferon, type 2 interferon, T interferon, T cell interferon, mitogen induced interferon, pH2-labile interferon, macrophage-activating factor, MAF Immunogen E. coli-expressed IFN-γ Conjugate PACBLU (Pacific Blue™) Buffer Formulation Phosphate buffered saline containing Clonality Monoclonal Concentration […]

The cytokine Interferon-γ (IFN-γ) exerts powerful immunoregulatory effects on the adaptive immune system and also enhances functions of the neutrophil (PMN). The clinical use of IFN-γ has been driven by the finding that its administration to patients with chronic granulomatous disease (CGD) results in decreased incidence and severity of infections. However, IFN-γ has no effect […]

Idiopathic pulmonary fibrosis (IPF), a fibrosing interstitial lung disease, predominantly affects the elderly and is associated with a high mortality risk. Nintedanib, a tyrosine kinase inhibitor, significantly reduces IPF progression. However, data on the tolerability and efficacy of nintedanib in the elderly with IPF are limited. Therefore, this study aimed to examine the tolerability and […]

Background: Anti-fibrotic therapies slow down the progression of idiopathic pulmonary fibrosis (IPF) by reducing lung function decline. However, little is known about the impact of anti-fibrotic drugs on health-related quality of life. This study was aimed to determine the influence of anti-fibrotic treatment on patients’ reported symptoms, along with their experiences and expectations of the […]

Name Mouse IFN-gamma ELISA Kit (GWB-SKR076) Related Product Names Interferon gamma Kit Range 23-1500 pg/mL Sensitivity 23 pg/mL Sample Type Cell lysates, sera and plasma Kit Detection Colorimetric 450 nm Gene Symbol IFNG Gene Family IFN Gene Fullname interferon gamma Gene id 15978 Alias Symbols Ifg, IFN-g, IFN-gamma, Interferon gamma Swissprot ID P01580 Protein Name […]

We compliment Christine Ho and colleagues on their study comparing three tests for latent tuberculosis infection in more than 22 000 individuals. 1 Ho CS Feng PI Narita M et al. Comparison of three tests for latent tuberculosis infection in high-risk people in the USA: an observational cohort study. They concluded that IFNγ release assays should […]

A IFN-gamma e6e3lA1 A: alpha bundles X: Ferritin/Heme oxygenase/4-helical cytokines H: 4-helical cytokines (From Topology) T: 4-helical cytokines F: IFN-gamma ECOD (1.6) B IFN-gamma e6e3lB1 A: alpha bundles X: Ferritin/Heme oxygenase/4-helical cytokines H: 4-helical cytokines (From Topology) T: 4-helical cytokines F: IFN-gamma ECOD (1.6) E Tissue_fac e6e3lE2 A: beta sandwiches X: Immunoglobulin-like beta-sandwich H: Immunoglobulin-related […]

Humans experience the world in three dimensions, but a collaboration in Japan has developed a way to create synthetic dimensions to better understand the fundamental laws of the Universe and possibly apply them to advanced technologies. They published their results on January 28, 2022 in Science Advances. “The concept of dimensionality has become a central […]

Harari S.a,b · Pesci A.c · Albera C.d · Poletti V.e,f · Amici C.g · Crespi G.h · Campolo B.h · Vancheri C.i · on behalf of the FIBRONET study group Author affiliations aDepartment of Clinical Sciences and Community Health, University of Milan, […]

To repeat the success of CAR-T therapies in blood cancers, a key direction for solid tumor research focuses on enabling the engineered immune cells to better target those tumors. Now, a group of scientists in Italy has proposed a method to do just that. Sugar-based structures called N-glycans, which are expressed on the surface of pancreatic […]

Pill Identifier Search AMNEAL 1642 Pill with imprint AMNEAL 1642 is White, Capsule-shape and has been identified as Pirfenidone 267 mg. It is supplied by Amneal Pharmaceuticals LLC. Pirfenidone is used in the treatment of idiopathic pulmonary fibrosis and belongs to the drug class miscellaneous uncategorized agents. Risk cannot be ruled out during pregnancy. Pirfenidone […]

Applications: ELISA Reactivity: Mouse Note: FOR RESEARCH USE ONLY (RUO). Sensitivity: 28.13 pg/mL Detection Limit: 46.88~3000pg/mL Short Description: This MI Gamma/CXCL9 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). Gene Symbol: Cxcl9 Gene ID: 17329 Uniprot ID: CXCL9_MOUSE […]

This report displays the potential drug interactions for the following 2 drugs: interferon gamma-1b Paracetamol (acetaminophen) Edit list (add/remove drugs) Interactions between your drugs No interactions were found between interferon gamma-1b and Paracetamol. This does not necessarily mean no interactions exist. Always consult your healthcare provider. interferon gamma-1b A total of 143 drugs are known […]

Merkel cell polyomavirus (MCPyV) is the causative agent of an aggressive skin tumor, Merkel cell carcinoma (MCC). The viral genome is integrated into the tumor genome and harbors nonsense mutations in the helicase domain of large T antigen (LTAg). However, the molecular mechanisms by which the viral genome gains the tumor-specific mutations remain to be […]