lorazepam-drug-study.docx – GENERI C NAME Lorazep am BRAN D NAME Ativan DOSAGE & ROUTE CLASSIFIC ATION INDICATION CONTRAINDICATI ON MECHANISM

GENERI
C NAME
BRAN
D
NAME
DOSAGE
& ROUTE
CLASSIFIC
ATION
INDICATION
CONTRAINDICATI
ON
MECHANISM OF
ACTION
SIDE EFFECTS
NURSING CONSIDERATION
Lorazep
am
Ativan
Antianxiet
y
Adult: PO
2–6 mg/d
in divided
doses
(max: 10
mg/d)
Geriatric:
PO 0.5–1
mg/d
(max:
2
mg/d)
Child:
PO/IV 0.05
mg/kg q4–
8h (max: 2
mg/dose)
Insomnia
Adult: PO
2–4 mg at
•BENZODI
AZIPINE
•ANXIOLY
TIC
•SEDATIV
E-
HYPNOTIC
Indicated for the
management of
anxiety disorders
or for the short-
term relief of the
symptoms
of
anxiety
or
anxiety
associated with
depressive
symptoms.
Contraindicated in
patients
with
hypersensitivity to
benzodiazepines
or
to
any
components
of
the formulation,
acute
narrow-
angle glaucoma.
• low amount of
albumin proteins
in the blood.
•suicidal
thoughts.
•alcohol
intoxication.
•drug abuse.
•asthma.
•liver problems.
It
binds
to
benzodiazepine
receptors on the
postsynaptic
GABA-A ligand-
gated
chloride
channel neuron
at several sites
within the central
nervous system
(CNS).
It
works
by
increasing
the
levels
of
a
calming
chemical,
gamma-amino-
butyric-acid
(GABA), in your
brain. Depending
on your health
condition,
this
can make you
feel
calmer,
CNS:
Anterograde
amnesia, drowsiness,
sedation,
dizziness,
weakness,
unsteadiness,
disorientation,