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Idiopathic Pulmonary Fibrosis

13Oct

Sec. 345 IAC 2.5-1-9 – “Bovine interferon gamma assay” defined | State Regulations | US Law

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§ 345 IAC 2.5-1-9. “Bovine interferon gamma assay” defined Authority: IC 15-17-3-21 Affected: IC 15-17 Sec. 9. “Bovine interferon gamma assay” means an official supplemental diagnostic test approved by the state veterinarian. (Indiana State Board of Animal Health; 345 IAC 2.5-1-9; filed Apr 13, 2005, 12:30 p.m.: 28 IR 2673; readopted filed Nov 1, 2011, […]

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12Oct

Computer Retrieval of Information on Scientific Projects, Abstract Display

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CRISP – Computer Retrieval of Information on Scientific Projects, Abstract Display Abstract Grant Number: 2R44AI060043-02A1 Project Title: Long Acting IFN-gamma for Treating Immunodeficiencies PI Information: Name Email Title COX, GEORGE N. Abstract: DESCRIPTION (provided by applicant): Interferon-gamma is a T cell-derived cytokine that exhibits anti-viral and immunomodulatory effects on many cell types. Recombinant human […]

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11Oct

IFNGR1 antibody | Anti-IFNGR1 | stjohnslabs

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Host: Rabbit Applications: WB, IHC-P, ELISA Reactivity: Human Note: FOR RESEARCH USE ONLY (RUO). Short Description: Rabbit polyclonal antibody Anti-Interferon gamma receptor 1 (101-150 aa, Internal) is suitable for use in Western Blot, Immunohistochemistry and ELISA. Clonality: Polyclonal Conjugation: Unconjugated Isotype: IgG Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. […]

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11Oct

Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation.

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Fresh human peripheral blood lymphocytes were induced with desacetylthymosin -alpha 1 and staphylococcal enterotoxin B. The induced gamma interferon (or IFN-gamma, immune interferon, type II interferon) was purified to homogeneity utilizing controlled-pore glass, concanavalin A-Sepharose, Bio-Gel P100, or Sephacryl S-200, and reversed phase high performance liquid chromatography. This procedure resulted in two active species with […]

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10Oct

Interleukin-4 and interferon-gamma synergistically increase secretory component gene expression, but are additive in stimulating secretory immunoglobulin A release by Calu-3 airway epithelial cells

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TY – JOUR T1 – Interleukin-4 and interferon-gamma synergistically increase secretory component gene expression, but are additive in stimulating secretory immunoglobulin A release by Calu-3 airway epithelial cells AU – Loman, S. AU – Jansen, H. M. AU – Out, T. A. AU – Lutter, R. PY – 1999 Y1 – 1999 N2 – Interleukin-4 […]

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8Oct

Development of an Interferon Gamma Response-Related Signature for Prediction of Survival in Clear Cell Renal Cell Carcinoma

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Background: Interferon plays a crucial role in the pathogenesis and progression of tumors. Clear cell renal cell carcinoma (ccRCC) represents a prevalent malignant urinary system tumor. An effective predictive model is required to evaluate the prognosis of patients to optimize treatment. Materials and methods: RNA-sequencing data and clinicopathological data from TCGA were involved in this […]

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7Oct

Human schistosomiasis mansoni: intensity of infection differentially affects the production of interleukin-10, interferon-$gamma; and interleukin-13 by soluble egg antigen or adult worm antigen stimulated cultures

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Célia Maria V. VENDRAME ◽   Márcia Dias T. CARVALHO ◽   Célia Regina F. YAMAMOTO ◽   Maria Cristina NAKHLE ◽   Silvino Alves CARVALHO ◽   …   The circumoval precipitin test (COPT), enzyme-linked immunosorbent assay (ELISA) and the immunoblotting anti-adult worm antigen (AWA) and soluble egg antigen (SEA) tests were applied to […]

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7Oct

Alterations of interferon-gamma-induced monocyte activation by immunomodulating compounds determined by neopterin production

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Gelderblom, H., Pauli, G., Rokos, K. and Rokos, H.. “Alterations of interferon-gamma-induced monocyte activation by immunomodulating compounds determined by neopterin production”. 9 Zurich, Switzerland, September 3–8, 1989, edited by Hans-Christoph Curtius, Sandro Ghisla and Nenad Blau, Berlin, Boston: De Gruyter, 2019, pp. 519-522. doi.org/10.1515/9783110889000-097 Gelderblom, H., Pauli, G., Rokos, K. & Rokos, H. (2019). Alterations […]

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30Sep

Multicenter phase II trial of nintedanib plus docetaxel in second-line treatment in advanced non-squamous non-small cell lung cancer patients refractory to first-line platin-based chemotherapy (REFRACT GFPC 02-15 study)

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Comments Off on Multicenter phase II trial of nintedanib plus docetaxel in second-line treatment in advanced non-squamous non-small cell lung cancer patients refractory to first-line platin-based chemotherapy (REFRACT GFPC 02-15 study)

Introduction: Advanced non-squamous non-small cell lung cancer (NsqNSCLC) progressing at the induction of a first-line of platin-based chemotherapy is a subgroup of patients with poor prognosis and few second-line treatment options. Materials and methods: This single-stage phase II prospective multicenter open-label trial performed in platin-based refractory (i.e. progressing during induction phase of first-line platin-based chemotherapy) […]

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29Sep

Analysis of tumor necrosis factor-alpha, transforming growth factor-beta, interleukin-10, IL-6, and interferon-gamma gene polymorphisms in patients with chronic periodontitis.

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Cytokine gene polymorphisms may have an impact on the susceptibility to and progression of chronic periodontitis. In this study, we analyzed the -1082 interleukin-10 (IL-10), -308 tumor necrosis factor-alpha (TNF-alpha), transforming growth factor-beta 1 (TGF-beta1) (codons 10 and 25), -174IL-6, and +874 interferon-gamma (IFN-gamma) gene single-nucleotide polymorphisms in a cohort of patients with chronic periodontal […]

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28Sep

AB_148087 Search – The Antibody Registry

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AB_148087 Search – The Antibody Registry From 3-4pm PST on Monday January 27th, 2014 our search services will be offline to upgrade hardware. We apologize for any inconvenience. Showing 1 – 2 results out of 2 with the query: AB_148087 Note: If possible, search using a catalog number. Avoid using “llc”, “inc”, or any other […]

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26Sep

Evaluation of a new interferon gamma release assay, in comparison to tuberculin skin tests and quantiferon tuberculosis goldplus for the detection of latent tuberculosis infection in children from a high tuberculosis burden setting

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Background: : Detection of latent tuberculosis infection (LTBI) in children, exposed to tuberculosis (TB) infections, followed by appropriate treatment, could be instrumental in reducing TB burden. Interferon Gamma release assays (IGRA) have higher specificity than tuberculin skin tests (TST), hence are more effective option for diagnosis. Hence, the present study was aimed to diagnose the […]

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25Sep

Temas para TCC The Antiviral Response to Gamma Interferon

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The Antiviral Response to Gamma Interferon AUTOR(ES) Costa-Pereira, Ana P. FONTE American Society for Microbiology RESUMO A role for alpha/beta interferon (IFN-α/β) in the IFN-γ antiviral response has long been suggested. Accordingly, possible roles for autocrine or double-stranded-RNA (dsRNA)-induced IFN-α/β in the IFN-γ response were investigated. Use was made of wild-type and a variety of […]

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25Sep

Structure of the human immune interferon gene.

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Sequence determination of cloned cDNAs and genes of the three classes of interferon (IFN-alpha, -beta and -gamma) has revealed more than a dozen members of the human IFN-alpha gene family and a single gene for IFN-beta. These genes are found on chromosome 9 and contain no introns. We recently reported that the 146-amino acid sequence […]

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25Sep

Temas para TCC Fever and acute phase response induced in rabbits by human recombinant interferon-gamma.

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Fever and acute phase response induced in rabbits by human recombinant interferon-gamma. AUTOR(ES) Morimoto, A RESUMO 1. Intravenous (I.V.) and intracerebroventricular (I.C.V.) injections of human recombinant interferon-gamma (IFN-gamma) produced dose-dependent fevers in rabbits. The fever induced by I.V. injection was monophasic and the maximum elevation occurred 80-110 min after injection. The fever induced by I.C.V. […]

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23Sep

IFNG – PrimePCR Assay and Template | Life Science

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Control assays and synthetic DNA templates were designed to facilitate the assessment of the key experimental factors impacting your real-time PCR results. DNA Contamination Control AssayUse the PrimePCR DNA contamination control assay to determine if genomic DNA (gDNA) is present in a sample at a level that may affect PCR results. This assay may also […]

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21Sep

PIRFENIDONE LIMITS TH2 FIBROGENIC RESPONSE IN EXPERIMENTAL LIVER FIBROSIS

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Please use this identifier to cite or link to this item: hdl.handle.net/20.500.12104/35779 Title:  PIRFENIDONE LIMITS TH2 FIBROGENIC RESPONSE IN EXPERIMENTAL LIVER FIBROSIS Author:  Novarro-Partida, JMarquez-Aguirre, AMartinez-Rizo, AGonzalez-Cuevas, JGolvez-Gostelum, FJBueno-Topete, MArmendariz-Borunda, J Issue Date:  2008 Publisher:  JOHN WILEY & SONS INC URI:  hdl.handle.net/20.500.12104/35779 ISSN:  0270-9139 Appears in Collections: Producción científica UdeG Files in This Item: There […]

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27Aug

Effect of Pirfenidone vs Nintedanib on Acute Exacerbation of Idiopathic Pulmonary Fibrosis

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In patients receiving antifibrotic agents, a reduction in the risk of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) may be greater for pirfenidone than for nintedanib, according to the results of a retrospective study published in Respiratory Medicine. AE-IPF is a fatal event that can occur during the clinical course of IPF; however, data from […]

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17Aug

Early phase lung drug trial proves hopeful for heart failure patients

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An early phase trial, funded by the National Institute for Health Research (NIHR), has shown that a drug currently used to treat lung fibrosis may also help patients with a common form of heart failure. The trial found that pirfenidone could offer a viable treatment for heart failure with preserved ejection fraction (HFpEF). The study […]

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