Treatment with two approved antifibrotics did not lessen a risk of death in recently hospitalized idiopathic pulmonary fibrosis (IPF) patients, but those using either therapy who went on to be discharged were more likely to live longer than those who were not, a database study reported. “To our knowledge, this is the first use of real-world […]

© iStock/magicmine A drug currently used to treat lung fibrosis could be repurposed to treat heart failure patients, an early phase trial has suggested. Doctors and scientists from the University of Manchester and Manchester University NHS Foundation Trust, in collaboration with Liverpool Clinical Trials Centre, trialled the drug pirfenidone and found that it could offer […]

Two approved antifibrotic IPF therapies, Ofev (nintedanib) and Esbriet (pirfenidone), were available during the study period, and participants were … Source link

Pirfenidone then reduced that scarring.” Pirfenidone works by inhibiting the biological processes involved in scar formation. The study enrolled patients … Source link

… (around $12,888), with the anti-fibrotic therapies Esbriet (pirfenidone) and Ofev (nintedanib) accounting for nearly 85% of total ILD medication costs. Source link

The retrospective study evaluated 262 patients with IPF who received pirfenidone or nintedanib — 2 antifibrotic agents currently in use that have similar … Source link

















