Kratom works by activating the brain's opioid receptors. In different amounts, this can produce various effects from increased energy to euphoria, analgesia (via British Journal of Pain), and even sedation if ingested in excess, according to Mayo Clinic. Alternatively, some individuals use it to relieve symptoms of opioid withdrawal.

It's easy to assume that plant-based products don't pose any risks to human health. However, between 2011 and 2017, about 1,800 kratom-related incidents were reported to poison control centers across the country, including cases of infant exposure. Side effects of the supplement include weight loss, muscle pain, liver damage, dizziness, vomiting, and more. In more severe cases, kratom use can lead to hallucinations, delusion, addiction, depression, impaired breathing, seizure, coma, or death. The supplement has also been shown to have negative interactions with certain prescription medications that may subsequently impact brain function. Even if a person is attempting to take a small dose, experts report that the potency of the plant can vary. This makes it difficult to know the exact dosage — or the related side effects a person may experience.

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