Drug-Drug Interactions: AMITRIPTYLINE+MECOBALAMINSR may interact with pain killers (tramadol, trazodone, hydrocodone, oxycodone, acetaminophen), an antidepressant (bupropion, duloxetine, fluoxetine, sertraline), antihistamine (diphenhydramine, cetirizine), sedatives (zolpidem), muscle relaxant (cyclobenzaprine), anti-convulsant (gabapentin, lamotrigine, escitalopram, pregabalin, topiramate), anti-thyroid (levothyroxine), and anti-anxiety (alprazolam).

Drug-Food Interactions: Avoid alcohol consumption while taking AMITRIPTYLINE+MECOBALAMINSR as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: AMITRIPTYLINE+MECOBALAMINSR may have interactions with disease conditions such as heart problems, anticholinergic effects, depression, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, pheochromocytoma, neutropenia, kidney and liver problems.

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