Notes to editor

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This press release accompanies both a presentation and an ESC press conference at ESC Congress 2021. It does not necessarily reflect the opinion of the European Society of Cardiology.

Funding: The ENVISAGE-TAVI AF trial was funded by Daiichi-Sankyo

Disclosures: GD’s institution has received research grants from Daiichi-Sankyo and GD has lectured about this clinical condition.

References and notes

1ENVISAGE-TAVI AF: edoxaban vs. vitamin K antagonists after TAVI in patients with atrial fibrillation.

2 Dangas G et al. Edoxaban vs Vitamin K Antagonists for Atrial Fibrillation After Transcatheter Aortic Valve Replacement (ENVISAGE-TAVI AF). N Engl J Med. 10.1056/NEJMoa2111016

3Mack MJ, Leon MB, Thourani VH, et al. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients. N Engl J Med. 2019;380:1695–1705.

4Holmes DR, Nishimura RA, Grover FL, et al. Annual outcomes with transcatheter valve therapy: from the STS/ACC TVT Registry. J Am Coll Cardiol. 2015;66:2813–2823.

5Tarantini G, Lefèvre T, Terkelsen CJ, et al. One-year outcomes of a European transcatheter aortic valve implantation cohort according to surgical risk: subanalysis of the SOURCE 3 Registry. Circ Cardiovasc Interv. 2019;12:e006724.

6Reardon MJ, Van Mieghem NM, Popma JJ, et al. Surgical or transcatheter aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2017;376:1321–1331.

7Popma JJ, Deeb GM, Yakubov SJ, et al. Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients. N Engl J Med. 2019;380:1706–1715.

8Leon MB, Smith CR, Mack MJ, et al. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2016;374:1609–1620.

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