This report displays the potential drug interactions for the following 2 drugs:

  • diphenhydramine/phenylephrine
  • Mucinex D (guaifenesin/pseudoephedrine)

Edit list (add/remove drugs)

Interactions between your drugs

No interactions were found between diphenhydramine / phenylephrine and Mucinex D. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

diphenhydramine / phenylephrine

A total of
522 drugs
are known to interact with
diphenhydramine / phenylephrine.

  • Diphenhydramine / phenylephrine is in the drug class
    upper respiratory combinations.
  • Diphenhydramine / phenylephrine is used to treat the following conditions:

Mucinex D

A total of
153 drugs
are known to interact with
Mucinex D.

Drug and food interactions

No interactions were found. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition.
This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit.
It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy,
and can have potentially adverse consequences.

The recommended maximum number of medicines in the 'decongestants' category to be taken concurrently is usually one.
Your list includes two medicines belonging to the 'decongestants' category:

  • diphenhydramine/phenylephrine
  • Mucinex D (guaifenesin/pseudoephedrine)

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication.
This information does not take the place of talking to your doctor.
Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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