MEDICATION CARD – LILIAN THIMOTTI

POSTPARTUM

DIPHENHYDRAMINE BENADRYL

GENERIC NAME TRADE NAME

CLASSIFICATION

Therapeutic: Competes for H1-receptor sites on effector cells, thus blocking histamine release.

Pharmacologic: ANTIHISTAMINE; H1-RECEPTOR ANTAGONIST

Pregnancy Category: C

INDICATIONS Temporary symptomatic relief of various allergic conditions and to treat or prevent motion

sickness, vertigo, and reactions to blood or plasma in susceptible patients. Also used in anaphylaxis as

adjunct to epinephrine and other standard measures after acute symptoms have been controlled; in

treatment of parkinsonism and drug-induced extrapyramidal reactions; as a nonnarcotic cough

suppressant; as a sedative-hypnotic; and for treatment of intractable insomnia.

DOSAGE/RANGE

Route & Dosage

Allergy Symptoms, Antiparkinsonism, Motion Sickness, Nighttime Sedation

Adult: PO 25–50 mg t.i.d. or q.i.d. (max: 300 mg/d) IV/IM 10–50 mg q4–6h (max: 400 mg/d)

Child: PO/IV/IM 2–6 y, 6.25 mg q4–6h (max: 300 mg/24 h); 6–12 y, 12.5–25 mg q4–6h (max: 300 mg/24

h).

Nonproductive Cough

Adult: PO 25 mg q4–6h (max: 100 mg/d)

Child: PO 2–6 y, 6.25 mg q4–6h (max: 25 mg/24 h); 6–12 y, 12.5 mg q4–6h (max: 50 mg/24 h)

SIDE EFFECTS

CNS: Drowsiness, dizziness, headache, fatigue, disturbed coordination, tingling, heaviness and weakness

of hands, tremors, euphoria, nervousness, restlessness, insomnia; confusion; (especially in children):

excitement, fever. CV: Palpitation, tachycardia, mild hypotension or hypertension, cardiovascular

collapse. Special Senses: Tinnitus, vertigo, dry nose, throat, nasal stuffiness; blurred vision, diplopia,

photosensitivity, dry eyes. GI: Dry mouth, nausea, epigastric distress, anorexia, vomiting, constipation, or

diarrhea. Urogenital: Urinary frequency or retention, dysuria. Body as a Whole: Hypersensitivity (skin

rash, urticaria, photosensitivity, anaphylactic shock). Respiratory: Thickened bronchial secretions,

wheezing, sensation of chest tightness.

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