Product Description
PACKING:
192x60ml
COMPOSITION:
Each 5ml contains:
|
Paracetamol |
I.P. |
125 mg |
|
Phenylephrine Hydrochloride |
I.P. |
5 mg |
|
Chlorpheniramine Maleate |
I.P. |
1 mg |
DESCRIPTION:
COLD-GO contains an analgesic-antipyretic Paracetamol with decongestant Phenylephrine and an antihistamine Chlorpheniramine Maleate. Paracetamol is a para-aminophenol derivative, produces antipyresis by acting on the hypothalamic heat regulating center and analgesia by elevating the pain threshold. Phenylephrine Hydrochloride is a selective 1-adrenergic receptor agonist used primarily as a decongestant. Chlorpheniramine Maleate an alkylamine derivative is anti-histaminic that causes moderate degree of sedation.
MECHANISM OF ACTION:
Paracetamol works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Phenylephrine constricts the blood vessels in the nasal mucous membranes and allows the air passages to open up. The majority of the sympathomimetic action is due to direct stimulation of the adrenoceptors. Chlorpheniramine Maleate has sedative & anti-cholinergic actions, but lacks selectivity for the cough centre.
INDICATIONS:
Relief of nasal and upper respiratory congestions, common cold, runny nose, skin rashes or any other allergic manifestations and vasomotor rhinitis.
CONTRAINDICATIONS:
Hypersensitivity to any ingredient of the product.
SIDE EFFECTS:
Headache, dizziness, nausea, palpitations, restlessness.
DOSAGE:
As directed by the physician.
CAUTION:
Overdosage of paracetamol can cause liver damage.
STORAGE:
Keep away from children, Store in a cool, dry place. Protect from light.
PRESENTATION: 60ml bottle
