Venlafaxine - what dosage does everyone take on Effexor XR? My depression is back somewhat and I'm already on 300 mg. I was fine for a while!
Answers would really reassure me right now. Thanks in advance!


3 hours 27 minutes ago

I was on 225 mg for 20+ yrs. Now on 150 for anxiety.


2 hours 46 minutes ago

Hi, Randomgirl!
225mg is the maximum recommended daily dose except for severely depressed patients so a dose adjustment is likely not possible. How long have you been taking it? Antidepressants can "poop out" after long term use.
Talk to your doctor about a possible add-on medication like Abilify or Rexulti or a switch to a different medication.
Best regards and I hope you're feeling better soon.
PS, I took the 225mg/day dose for over seven years with Abilify added after a couple of years.

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