6Mar chapter 40 Flashcards | Quizlet Posted by: admin Categories: Pulmonary Embolism Comments Off on chapter 40 Flashcards | Quizlet chapter 40 Flashcards | Quizlet Prevent the formation of clots that inhibit circulation prevent platelet aggregation- uses: Prevent thrombosis in the arteries, Prevention of myocardial infarction or stroke for patients with familial history, Prevention of a stroke for patients having transient ischemic attacks (have TIA, will have stroke) attack and dissolve blood clots that have already formed- used to treat ischemic stroke 1. decreased circulation2. platelet aggregation on vessel wall3. blood coagulation what 3 things causes the formation of clot in artery or vein - platelets inhibit process- fibrin formation occurs- RBCs are trapped in fibrin mesh Platelet aggregation with fibrin that attaches to RBCs high alert anticoagulant that prevents venous thrombosis - administered subcutaneously and intravenously 1. bind with antithrombin III2. inhibit action of thrombin 3. inhibit conversion of fibrinogen to fibrin 4. inhibit clot formation what are the two lab values to look for while taking heparin PTT (partial thromboplastin time) lab value: 1.5 to 2 times control value of clots (control 60 to 70 seconds) aPTT (activated partial thromboplastin time) lab value: 30 to 85 seconds (control 20 to 35 seconds) protamine sulfate (use this if bleeding time is too long) what is the antidote for heparin anticoagulant, low molecular weight heparin that inactivates Xa factor- use: prevents DVT and acute PE after orthopedic or abdominal surgery - don't take with aspirin Anticoagulant, Vitamin K Antagonist that inhibits hepatic synthesis of vitamin k thus affecting the clotting factors II, VII, IX, and X what lab values should be monitored while taking warfarin prothrombin time - measures the time of clot International Normalized Ratio - a calculation based on the PT used to monitor patients using blood thinners how is warfarin administered how many days does it take for warfarin (Coumadin) to reach the blood antidote for warfarin (takes 24 to 48 hours to be effective) nursing interventions for heparin -Monitor PT, INR for warfarin, and aPTT for heparin before administering anticoagulant.-Examine patient's nose, mouth, skin, urine for bleeding.-Teach patient to inform dentist when taking an anticoagulant.-Advise patient to use a soft toothbrush to prevent bleeding gums.-Advise patient to avoid large amounts of green, leafy vegetables or be consistent with intake. Antiplatelet that is effective and inexpensive treatment for suppressing platelet aggregation- has low dose therapy of 81mg or baby - action: inhibit cyclooxygenase, an enzyme needed by platelets to synthesize thromboxane A2 (TxA2)- use: Prevention of MI and thromboembolism, prevention and treatment of stroke Source link
rivaroxaban and sertraline.docx – Brand Name Xarelto Generic Rivaroxaban Brand Name Zoloft Generic Sertraline Classification Anticoagulants