Which covariates include in the differential expression analysis

0

Hi,

I'm running deseq2 to find differentially expressed genes between patients and controls. The problem is that I have many different variables that could have an effect on the expressed genes, such as age, gender, etc. How can I know which is the effect of those variables in the model? I know that normally the model includes all of the variables as covariates, but it can't be that it also includes some bias?

Maybe this is a naïve question, but I'm very new to these kind of analysis.

Thank you very much,
Lluc


covariates


expression


differential


deseq2


analysis


R

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