I'm merging multiple RNAseq datasets and, after differential expression analysis with
DESeq2, I got a very weird volcano plot... there're some genes than seem extremely differentially expressed with a logFC sooo low (-20 ?!).
I don't understand if I missconsidering something or I'm merging these datasets in an incorrect way... what I've done is simply read each matrix counts and concatenate them. Any idea, please?