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12 hours ago by

Is there a monotonous relationship between the number of SVs one estimates (sva package), and the number of DE genes one should get as significant?
In other words, is it true that the more SVs are used, the more DE genes should be significant?

(I understand that a large number of significantly DE genes is not a positive value in itself; and the more SVs one estimates, the more likely the chance to overfit. Just for understanding's sake )

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modified 5 hours ago

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12 hours ago
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Sam50



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