I have two data setes, in which some samples are from the same patients (library preparation has not been performed at the same time), and some samples are not from the same patients but we have 4 cell lines definitely from the sample patients in two plates (higlighted in yellow)

This is the samples and controls are in yellow

![enter image description here][1]

[1]: i.ibb.co/Tr7KZfZ/Untitled.png

You imagine I have two plates like this

How I know if the these plates are replicable? Can I just simply look at the correlation of gene expression of these 4 cell lines between two plates?

Thank you for any thoughts

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