gravatar for J.F.Jiang

2 hours ago by


Hi all,

Distinguishing germline variants, especially those pathogenic ones, are of great importance, since these variants might increase the cancer susceptibility in other family members.

It is quite challenge when blood sample/matched normal is absence, leaving a lot of variants with zygosity/Allele frequency around 0.5.

Is there any public tool to determine the origin of the variants?



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