i'm just beginned graduate school student
i have bunch of panel of normal files that made by lab predecessor(senior) who already graduated
and those are hg19 coordinated.
the looks like this :
#CHROM POS REF ALT DPsum;DPn;VARsum;VARn;VAFpct 1 10003 A AC 4166;36;6;6;0.14 ......
but nowadays quite many tools support hg38 and tools like Mutect2 they highly recommend using hg38 reference
i wanna change my hg19 coordinated PON file to hg38 coordinated PON file if it's possible but i can't find appropriate way
i don't have any BAM or fastq file that used for PON
but i really need it for VCF post filtering
thanks for in advance for any reply