P value signficancy

1

I need a suggestion ,i analyzed a GEO data set by GEO2R.Where i found 4435 gene that are signficant for adj.p.value.I want to find out the upregulated and down regulated gene from that.So how can i find that? Moreover i gave adj.p.value <0.05.If i give the range <0.01,so will i get more signficant gene for that?


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I want to find out the upregulated and down regulated gene from
that.So how can i find that?

Please refer to the log [base 2] fold change (log2fc):

  • negative log2fc, down-regulated
  • positive log2fc, up-regulated

Moreover i gave adj.p.value <0.05.If i give the range <0.01,so will i
get more signficant gene for that?

Yes, indeed. Better to say 'statistically significant', though.

Kevin


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