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2 hours ago by

I performed a GO enrichment analysis for a list of DE genes. In the end, I got ~20 GO terms enriched. When I check the DE gene names under each GO term, it appears that almost all the genes have the same names or isoforms so it is reasonable that they have the same 'GO labels'...What I expect in a GO enrichment test is that a spectrum of different genes belonging to a common category would cluster together, in my case it is not...

I am totally lost at this point. Does it mean my result is not informative at all since it only reflects the DE pattern of a very limited number of genes? Is there a way to improve this?


modified 2 hours ago

2 hours ago


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