Hi all,

I'm struggling to make sense of some GO-term enrichments results I have. For the disease (an inflammatory disease) I'm studying, I get GO terms which don't really seem relevant to it. For example, I have a lot of cancer terms and I'm thinking these may reflect increased proliferation, but how can I justify this in a paper? I also have a lot of terms related to specific infections (eg. HPV and CMV) which may reflect inflammation, but I run into the same problem - how can this be justified?

I have tried doing literature searches for the terms themselves, but the papers are very specific to the disease studied and I am unsure how to apply it to my disease of interest.

Thanks!



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