Job description: Postdoc positions are available at the Mount Sinai School of Medicine (Top-20 medical school in the US) in New York City. Our lab is part of the Department of Genetics and Genomic Sciences.

Our lab (long read sequencing + experiment + computation) pioneered the fast growing field of bacterial epigenomics (Nature Biotechnology, 2012; Nature Reviews Genetics, 2018). We also pioneered the use of DNA methylation for high resolution microbiome analysis (Nature Biotechnology, 2018; Nature Methods, 2021). In addition, we use long read sequencing to study the human genome, epigenome and transcriptome (Genome Research, 2018; Nature Genetics, 2019). We have unique expertise in the use of third generation long read sequencing (Single Molecule Real-Time by PacBio, and Oxford Nanopore sequencing technology).

Recent publications: Nature Methods, 2021 (in press) * Nature Microbiology, 2020 * Trends in Microbiology, 2020 * Nature Genetics, 2019 * Nature Communications, 2019 * Nature Reviews Genetics, 2018 * Nature Biotechnology, 2018 * Genome Research, 2018 * Nature, 2016 * Cell Reports, 2016 * Nature Communications, 2015 * PLoS Genetics, 2015 * Nature Communications, 2014 * Molecular Psychiatry, 2014 * PLoS Genetics, 2013 * PLoS Computational Biology, 2013 * Genome Research, 2012 * Nature Biotechnology, 2012

Lab page with details:

We are looking for highly motivated candidates for multiple PostDoc Fellow positions on both novel Technology Development, Disease Systems Biology and Precision Medicine. Three research sub-directions

1) Long reads based epigenomics: Epigenomics and epigenetics of pathogens and human for the discovery of novel regulators, novel mechanisms and novel drug targets, with a focus on infectious diseases, human brains and immune system.

2) Long reads based microbiomics: Novel technology for, and its applications to, high resolution characterization of gut microbiome and its important roles in multiple human diseases.

3) Long reads based transcriptomics. Novel technology for resolving complex splicing in human genome both in development and human diseases with a focus on brain and immune disorders.

Successful candidates will have unique opportunities to i) build on our unique expertise in third-generation long read sequencing, large scale collection of clinically relevant samples and a strong network of collaborators, ii) take the lead role in projects developing cutting edge, pioneering genomic and epigenomics technologies in the context of innovative applications with high biological, biomedical and clinical impact. Compensations for successful candidates are highly competitive. Subsidized housing (in New York City) is also available.

Requirements: 1) Candidates with computational or experimental background are both welcomed. 2a) Candidates with computational background are expected to have solid training in bioinformatics, genomics, epigenomics transcriptomics, or metagenomics, 2b) Candidates with molecular biology skills are expected to have solid experience in bacterial genetics. 3) Ability to learn and master new technologies and skills, 4) Abilities to lead an independent research direction while adapting to a collaborative environment, 5) An innovative yet critical thinker.

How to apply: Please send the following to [email protected] (preferred) or [email protected] : 1) A brief cover letter, 2) CV with a list of publications, 3) PDF files for the papers in which you are first or co-first author.

Thank you for the interests!

Gang Fang, Associate Professor, Genetics and Genomics, Icahn School of Medicine at Mount Sinai

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