gravatar for asalimih

9 hours ago by

Hello,
I am using TCGA RNA-Seq data for a neural net method. I have splitted the data to train and test set. how do i normalize count data of train and test set without data leakage using limma?
My Idea is I might be able to normalize the train set using limma+voom method first and then use the parameters calculated by voom on train set(E and weights) to normalize the test set. however I couldn't realize how?

any help would be greatly appreciated.



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