K-mer usage in metagenome assemblies
Hello just want to ask what should be the considerations at choosing a specific k-mer size on metagenome assemblies pipelines (particularly based on de Bruijn graphs)? I have read an issue here github.com/ablab/spades/issues/251 where coverage seems to be a great determinant on the k-mer choose, but i want to know more, what are your recomendations?
Some researches have told me that a good practice is to dont modify the k-mer size of the fragments unless one have idea of what the result is going to be.
so, what are your considerations?
• 222 views