Hi there, I have been running survival analysis on individual genes of interest. Firstly, I divided them into two groups: Up-regulated and Down-regulated gene. And then, I run SA on each them. This is one of the many results I got.
I set the event: die =1, surival=0. To HR >1, it is easy to interpret, but with HR<1, e.g like this one, I dont know what it means? To me, I guess, down-regulation is Ref, and up-regulation's Harzard ratio of 0.758. It implies that up-regulated MAP2K4 is significantly associated with worse outcome than down-regulated MAP2K4 ! Is it right?