Insert size 350bp vs 400bp, any major downstream difference?

2 hours ago by

Germany

Hello!

I have two data sets one from HiSeq4000 with an insert size of 350bp and another set of reads from NovaSeq with average 400bp. I am wondering if I should have any reasons to belive there would be major consequences of this difference down the line.

Both sets of reads have the same length (150bp).