How to identify cell types using addModuleScore function?

1

Hello, there,

I am learning single-cell RNA-seq analysis using Seurat package. I have clustered cells into 12 clusters. Next, I want to identify the cell types of these cell clusters.

I read some paper using addModuleScore function based on the known cell markers. I did not find any example.

however, I do not know how to do identify cell types based on the scores as one cell cluster has several cell type scores.
For example, cell cluster one got an average of 0.5 in stem cell score and 0.6 in bronchial epithelial cell score,should the cell cluster one be considered as bronchial epithelial cell?

Need your help very much

Thank you very much


single cell RNA-seq

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