Hi every one,
I am wondering if anyone knows how to find cross-tissue communication signaling using gene expression data set. I have a gene expression profile of two different but inter-connected tissue. I want to get an idea of how these tissues are communicating at the molecular level.
So far, I have done differential expression analysis and enrichment analysis for both tissues using R. I found pathways commonly and differently regulated by both tissues. I have a hypothesis I would like to prove, but I don't know how to approach /study the communications between two tissue using transcriptomics?
I am kind of new to bioinformatics, sorry if I am damping a silly question here. Please also suggest to me what algorism in R helps me?
Thank you so much!