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2 hours ago by

Hi, I am doing now some analyses that require knowledge of the distance from some variant (and invatiant) positions in VCF files to the closest genomic feature reported on a separate GFF file.

I am currently doing so by processing these two files as spreadsheets and calculating these distances with some R code, but as you can imagine this is probably suboptimal, messy, and prone to errors.

I am assuming that there is probably a package on R Bioconductor or Python that allows to generate a dataset of genomic positions taken from a VCF and distances to different genomic features in GFF files, but so far I haven't found anything.

Do you have any recommendation on how to handle this?

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