edgeR batch correction

0

Hi all,

I have 2 groups (experiment vs control) 4 samples per each group. The setup is like this:

enter image description here

I did MDS plot to see how my samples are clustered.
enter image description here

Considering that experimental (hypoxic) replicates are far from each other, do I need to do batch correction here? If yes, what would be best approach here?
I would appreciate any help/explanation of what's happening here. Thank you!


edger


batch

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