I have a list of differentially expressed genes from a proteomic analysis of the secreted fraction of cells in culture. My supervisor has manually curated a list of genes which don't have a peptide signal and others that have it.
I was wondering if I could do this unbiased. I went trough GO terms but I couldn't find the relevant category.
Is there any database (ideally accessible with a R/Biocondcutor package) that I could use to label proteins/genes that have/don't have the signal peptide driving their synthesis in the RER??
Best regards and ++ for teleworking in the mist of covid2019!!!