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2 hours ago by


Hi guys, suppose you are analysing acetylation Chip-Seq data. You have a list of peaks (with associated reads) in some genomic regions. Then you annotate the peaks to the nearest gene. At this point you have many peaks to the same gene name. How do you collapse this information to a single one in terms of reads? Do you take the sum of the reads for all the peaks of that gene? Do you take the mean? The median? It is a crude analysis just to have one single number of reads for that gene in order to perform differential "expression" like for RNA-Seq. Thank you in advance


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2 hours ago


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