Thanks for you reply. In the answer that I linked in my original question, you say that A is the minor allele is ambiguous if we do not add any strand information (i.e. A on the + strand/ forward strand). That I understand.

What I do not understand is how a A/T SNP differs in that regard from a A/C SNP (which is considered to be non ambiguous). Isn't the situation the same?

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