Electroporation-Based Therapies for Cancer reviews electroporation-based clinical studies in hospitals for various
cancer treatments, including melanomas, head and neck cancers, chest wall breast carcinomas, and colorectal cancers, as
well as research studies in the lab using cell lines, primary cells, and animals. Cancer kills about one American per
minute, amounting to over 500,000 deaths in the United States and millions, worldwide, each year. There is a critical
need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring, and
chemo-resistant cancers, that do not respond well to current treatment regimen. An electrical-pulse-mediated, enhanced
drug delivery technique known as electroporation is one way to effectively treat these patients. This technique is
especially suitable for low- and middle-income countries, where lack of infrastructure and resources leads to cancer
diagnoses at late stages. This quick, safe, effective, economical, out-patient-based technique is a boon to these
patients for palliative and other care with enhanced quality of life. This book features discussions by
interdisciplinary authors-including practicing oncological surgeons, medical professionals, and academic and other
researchers-of the basics and clinical medical applications of electroporation. * Provides novel and recent clinical
applications of electrochemotherapy for various cancers, including melanomas, sarcomas, superficial extreme melanoma,
chest wall breast carcinoma, and colorectal cancers* Extensive study of a number of cell lines, including human breast
cancer, lung cancer, cervical cancer, leukemia, and mouse breast cancer using both reversible and irreversible
electroporation techniques* In vitro study of delivery of various commonly prescribed/administered breast cancer chemo
and hormone drugs, such as Doxorubicin, Paclitaxel, Bleomycin, and Tamoxifen



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