Review


doi: 10.1016/j.tvjl.2016.05.015.


Epub 2016 May 31.

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Review

J Impellizeri et al.


Vet J.


.

Abstract

Cancer treatments in veterinary medicine continue to evolve beyond the established standard therapies of surgery, chemotherapy and radiation therapy. New technologies in cancer therapy include a targeted mechanism to open the cell membrane based on electroporation, driving therapeutic agents, such as chemotherapy (electro-chemotherapy), for local control of cancer, or delivery of gene-based products (electro-gene therapy), directly into the cancer cell to achieve systemic control. This review examines electrochemotherapy and electro-gene therapy in veterinary medicine and considers future directions and applications.


Keywords:

DNA vaccines; Electro-gene therapy; Electrochemotherapy; Electroporation; Immunotherapy; Veterinary oncology.

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