This trial is comparing the effects and safety in treating men with prostate cancer between
irreversible electroporation and radical prostatectomy.
Four hundred and thirty-eight patients with localized prostate cancer will include in this
study. The clinical trial validation process will be as follows: (1) all patients are
randomly divided into two arms: arm 1, irreversible electroporation; group 2, radical
prostatectomy. The primary outcome is the 5-year free tumor progression rate.
Focal therapy(Irreversible Electroporation), Radical prostatectomy
Shanghai East Hospital, Tongji University School of Medicine
Not yet recruiting
Shanghai East Hospital
Results (where available)
Published on BioPortfolio: 2020-02-20T18:46:15-0500
Medical and Biotech [MESH] Definitions
A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).
Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.
A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).