Clinical Trials

  Summary July 2022, Nintendo (Japan) and Breathing Labs (Slovenia) have concluded a pilot clinical trial that has used gamified physiotherapy in a clinical environment and published its findings in a leading journal for pediatric pulmonology (links at the end of this doc). The present study showed that Nintendo Wii Fit provides additional benefits in […]

Material/Methods Thirty-eight in-patients with stroke (22 men, 16 women) were recruited for the study. Participants were randomly allocated into 2 groups: patients assigned to the GBE group (n=19), and the control group (n=19). The GBE group participated in a GBE program for 25 minutes a day, 3 days a week, during a 5 week period. […]

November 4th 2018, Wiley Publishing (New Jersey, U.S.) – Medical Journal Biomed Research International (Impact Factor = 2.6) has reported that “Breathing+ results were statistically significant and reliable for pulmonary function assessment and it will therefore be useful during rehabilitation to improve pulmonary function and clinical monitoring in stroke patients.” The study compared results of Breathing […]

Modifying cognitive bias as a treatment of anxiety disorders has been suggested as an alternative to less accessible and more expensive pharmacological and psychotherapeutic methods. Since it has been shown that breathing dysregulations play an important role in pathological reactions to stressful stimuli we suggest an alternative to currently used attention bias modification treatments through […]

PURPOSE: Breathing pattern retraining is frequently used for exertional dyspnea relief in adults with moderate to severe chronic obstructive pulmonary disease. However, there is contradictory evidence to support its use. The study objective was to compare 2 programs of prolonging expiratory time (pursed-lips breathing and expiratory muscle training) on dyspnea and functional performance. METHODS: A […]

A total of 28 healthy adults (ages 18 – 58; M = 31,61, SD = 11,50; 12 male, 16 female) were recruited via advertisement flyers. Written informed consent was obtained from all subjects prior to research. Subjects were seated in a relaxed position and attached to Galvanic Skin Response (GSR) sensor connected to Arduino computer […]

Pursed-lips breathing (PLB) is a maneuver that is frequently taught to patients with chronic obstructive pulmonary disease (COPD) in respiratory physiotherapy programs to improve breathing efficiency and better manage dyspnea during activities of daily living. Researchers first became interested in PLB when emphysema patients were clinically observed to breathe instinctively with the lips semi-closed in […]

51 healthy adults participated in a trial, and they were blindly randomized into two groups. Both groups were shown an image (Figure 3) and were instructed to apply the headset accordingly.     First group (active group, 26 subjects) were watching a youtube video (Psy: Gangnam style, length 4:13) which started and paused according to […]

In this paper, feasibility of web based breathing exercises for respiratory rehabilitation is examined. A system included visual guidance in a web browser and a microphone equipped headset for biofeedback and interaction. Feasibility was assessed in a controlled environment on 34 subjects with anxiety disorders that were not offered any help from the personnel. Weak […]

To examine the effect of pursed-lips breathing (PLB) on breathing pattern and respiratory mechanics, we studied 11 healthy subjects breathing with and without PLB at rest and during steady-state bicycle exercise. Six of these subjects took part in a second study, which compared the effects of PLB to expiratory resistive loading (ERL). PLB was found […]

Volunteers with anxiety disorder will participate in a 10-minute task in which a computer program would randomly select one graphic image from a wide variety of images representing accidents, phobias, tragedies and stressful situations.

In this research we observe human’s ability to recall visual stimuli according to their respiratory phase. To assess ability to recall visual stimuli Brown-Peterson task is used in a short term cued memory recall setup.  We show that the ability to recall visual stimuli does not noticeably relate to inspiration/expiration phasing, but that it more […]

In 2011 we have published results of preclinical trials evaluating functionality of a product Breathing+, it showed 97.1% reliability (10 subjects) when monitoring breathing frequency in non-guided free breathing and 100% reliability (10 subjects) when monitoring breathing frequency during interactive paced-breathing exercises. We also evaluated the breathing frequency detection systems noise elimination functionality which showed a reduction of 84.2 dB for stationary

This study was designed to clarify the effects of breathing with prolonged expiration on cardiopulmonary responses and autonomic nervous activity during incremental exercise. Eleven healthy men were randomly assigned to breathing mode: a prolonged expiration breathing with a 2-s inspired time and 4-s expired time and a spontaneous breathing without any constraints. Oxygen uptake (V(O2)), […]